CPAP has multiple physiologic advantages. In spontaneously breathing premature infants, it eases respiratory efforts by stenting the airway and the diaphragm. It maintains alveoli inflated, increases the functional residual capacity of the lung, and optimally matches ventilation with perfusion. Compared with mechanical ventilation and tracheal intubation, CPAP minimizes volutrauma (lung overdistention) and subsequent biotrauma. CPAP induces a favorable strain that stimulates lung growth when administered to animals over a prolonged time.
AEL 142 in Tift County, Georgia carried out its first Bubble CPAP flight on August 2